Date: 16/09/2018 10:56:31
From: mollwollfumble
ID: 1276832
Subject: How one can combine nanozymes and lectins together to profile cancer cells?

How one can combine nanozymes and lectins together to profile cancer cells?

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Date: 16/09/2018 17:30:16
From: mollwollfumble
ID: 1277048
Subject: re: How one can combine nanozymes and lectins together to profile cancer cells?

mollwollfumble said:


How one can combine nanozymes and lectins together to profile cancer cells?

No one has asked the obvious question yet. “In vitro or in vivo?”

Either.

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Date: 16/09/2018 17:36:28
From: Ian
ID: 1277056
Subject: re: How one can combine nanozymes and lectins together to profile cancer cells?

mollwollfumble said:


mollwollfumble said:

How one can combine nanozymes and lectins together to profile cancer cells?

No one has asked the obvious question yet. “In vitro or in vivo?”

Either.

Well we were all waiting for you to give some refs or put some context around the question.

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Date: 16/09/2018 17:50:33
From: mollwollfumble
ID: 1277067
Subject: re: How one can combine nanozymes and lectins together to profile cancer cells?

References? Like:

https://www.google.com.au/search?q=How+one+can+combine+nanozymes+and+lectins+together+to+profile+cancer+cells

https://scholar.google.com.au/scholar?hl=en&as_sdt=0%2C5&q=How+one+can+combine+nanozymes+and+lectins+together+to+profile+cancer+cells&btnG=

https://en.m.wikipedia.org/wiki/Artificial_enzyme#Nanozymes

https://en.m.wikipedia.org/wiki/Lectin

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Date: 16/09/2018 17:57:02
From: mollwollfumble
ID: 1277073
Subject: re: How one can combine nanozymes and lectins together to profile cancer cells?

mollwollfumble said:


References? Like:

https://www.google.com.au/search?q=How+one+can+combine+nanozymes+and+lectins+together+to+profile+cancer+cells

https://scholar.google.com.au/scholar?hl=en&as_sdt=0%2C5&q=How+one+can+combine+nanozymes+and+lectins+together+to+profile+cancer+cells&btnG=

https://en.m.wikipedia.org/wiki/Artificial_enzyme#Nanozymes

https://en.m.wikipedia.org/wiki/Lectin

Following up the first of these leads to:

“This project will develop new color-based biosensing tools for generating unique fingerprints of different
types of cancer cells. This robust profiling of mammalian cells will aid in the detection of cancer at early
stages of progression. To achieve this, the enzyme-like catalytic activity of the nanoparticles (NanoZyme) will
be employed for the generation of colorimetric response. These NanoZymes will be tagged with different
molecular recognition elements such as DNA aptamers, carbohydrate binding lectins, and antibodies. A sensor
array will then be created to obtain a fingerprint for each type of cell. This tool is not only likely to aid in
early detection of cancer but also developing personalized medicine, based on the unique biological profile of
individual cancer patients.”

Weerathunge, P., Ramanathan, R., Shukla, R., Sharma, TK., & Bansal, V. Anal. Chem. 86, 11937-11941 (2014). Sharma, TK., Ramanathan R., Weerathunge, P., Mohammadtaheri, M., Daima, HK., Shukla, R., & Bansal, V. Chem. Commun. 50, 15856-15859 (2014). Wang, X., Hu, Y. & Wei, H. Inorg. Chem. Front. 3, 41-60 (2016)
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