Actually, I think this deserves its own thread.
“A growing body of literature has…..highlighted that: (1) a dynamic measure capturing weight status changes (e.g., weight loss, large weight gain) is more predictive of disease and mortality than a static measure of weight status (e.g., baseline BMI) ; (2) obesity increases the risk of mortality more profoundly when it persists over the life course ; and (3) attributable mortality risk due to obesity is larger when using obesity trajectories rather than a static measure of obesity . These literatures are insightful in emphasizing the importance of dynamic BMI history on health and mortality, but life-course BMI dynamics have remained poorly characterized and it remains unclear how such dynamics relate to health and mortality.”
https://sci-hub.mksa.top/https://doi.org/10.1016/j.annepidem.2021.01.003
(I wonder if the mention of BMI in the topic will draw Rule out…)