Date: 2/01/2024 15:50:15
From: buffy
ID: 2109593
Subject: Diabetes research

I kinda wish they wouldn’t put this stuff in the general news when it’s still at the “look what we can make cells do in a petri dish” stage, but if this goes anywhere, it could be very good.

https://www.abc.net.au/news/2024-01-02/breakthrough-in-diabetes-treatment-research/103278156

And the paper

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Date: 2/01/2024 15:55:03
From: OCDC
ID: 2109595
Subject: re: Diabetes research

buffy said:

I kinda wish they wouldn’t put this stuff in the general news when it’s still at the “look what we can make cells do in a petri dish” stage, but if this goes anywhere, it could be very good.

https://www.abc.net.au/news/2024-01-02/breakthrough-in-diabetes-treatment-research/103278156

And the paper

Still, it’s nice to see Aussies in Nature. And the full-text article is free.

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Date: 2/01/2024 16:33:59
From: btm
ID: 2109623
Subject: re: Diabetes research

OCDC said:


buffy said:
I kinda wish they wouldn’t put this stuff in the general news when it’s still at the “look what we can make cells do in a petri dish” stage, but if this goes anywhere, it could be very good.

https://www.abc.net.au/news/2024-01-02/breakthrough-in-diabetes-treatment-research/103278156

And the paper

Still, it’s nice to see Aussies in Nature. And the full-text article is free.

I recall a paper published in the journal Cell in 2006 (DOI 10.1016/j.cell.2006.10.038) in which the researchers injected capsaicin into arteries supplying sensory nerves in β-cells, deactivating the cells and curing the diabetes, but as far as I can determine, nothing ever came of the research.

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Date: 2/01/2024 16:40:53
From: OCDC
ID: 2109628
Subject: re: Diabetes research

btm said:

OCDC said:
buffy said:
I kinda wish they wouldn’t put this stuff in the general news when it’s still at the “look what we can make cells do in a petri dish” stage, but if this goes anywhere, it could be very good.

https://www.abc.net.au/news/2024-01-02/breakthrough-in-diabetes-treatment-research/103278156

And the paper

Still, it’s nice to see Aussies in Nature. And the full-text article is free.
I recall a paper published in the journal Cell in 2006 (DOI 10.1016/j.cell.2006.10.038) in which the researchers injected capsaicin into arteries supplying sensory nerves in β-cells, deactivating the cells and curing the diabetes, but as far as I can determine, nothing ever came of the research.
adds to TBR list

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Date: 3/01/2024 05:23:09
From: mollwollfumble
ID: 2109775
Subject: re: Diabetes research

buffy said:


I kinda wish they wouldn’t put this stuff in the general news when it’s still at the “look what we can make cells do in a petri dish” stage, but if this goes anywhere, it could be very good.

https://www.abc.net.au/news/2024-01-02/breakthrough-in-diabetes-treatment-research/103278156

And the paper

> β-cells are a type of endocrine cell found in pancreatic islets that synthesize, store and release insulin. In type 1 diabetes (T1D), T-cells of the immune system selectively destroy the insulin-producing β-cells. Destruction of these cells leads to a lifelong dependence on exogenous insulin administration for survival. Consequently, there is an urgent need to identify novel therapies that stimulate β-cell growth and induce β-cell function. We and others have shown that pancreatic ductal progenitor cells are a promising source for regenerating β-cells for T1D owing to their inherent differentiation capacity.

A good start.

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Date: 3/01/2024 10:26:31
From: wookiemeister
ID: 2109828
Subject: re: Diabetes research

The researchers only gave alcohol to the mother rats on two days during their pregnancy. The rats’ blood alcohol concentration only reached 0.05%, and yet their male offspring became almost diabetic, with insulin levels reaching higher than expected to maintain normal blood sugar levels.9 Oct 2019

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Date: 3/01/2024 10:26:59
From: wookiemeister
ID: 2109829
Subject: re: Diabetes research

wookiemeister said:


The researchers only gave alcohol to the mother rats on two days during their pregnancy. The rats’ blood alcohol concentration only reached 0.05%, and yet their male offspring became almost diabetic, with insulin levels reaching higher than expected to maintain normal blood sugar levels.9 Oct 2019

See

FAS

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Date: 3/01/2024 10:27:34
From: wookiemeister
ID: 2109830
Subject: re: Diabetes research

wookiemeister said:


wookiemeister said:

The researchers only gave alcohol to the mother rats on two days during their pregnancy. The rats’ blood alcohol concentration only reached 0.05%, and yet their male offspring became almost diabetic, with insulin levels reaching higher than expected to maintain normal blood sugar levels.9 Oct 2019

See

FAS


Control alcohol use

Control diabetes

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