Date: 23/04/2013 16:06:33
From: purple
ID: 299776
Subject: GABA receptors

Due to something else, I’ve been having problems with insomnia.

I got some Dozile (Doxylamine succinate 25mg capsules) and have been taking one at night. I can’t find any research regrading this drug and GABA.

Today I bought ReDormin – valerian officinalis root 1.25g and humulus lupus fruit (hops) 360mg.
On researching I find valerian binds to the GABA receptors in a way that’s similar to benzodiazepine. which I don’t want. My GABA receptors are under enough stress as it is.

My question is will it be OK to use the valerian+
I have a support forum which says you shouldn’t take anything that binds to the receptors because it will take you longer to heal (from the original problem)

Thing is, if I don’t get sleep, I cannot cope with a bunch of other stuff.

I’m not naive enough to think because it’s a herb it is therefore safe.
thanks

Reply Quote
Date: 23/04/2013 16:10:33
From: poikilotherm
ID: 299778
Subject: re: GABA receptors

Doxylamine produces sedation via histamine receptors, not GABA.

In the bad news, effect of valerian officinalis to kick in can take up to 3 months in the few clinical trials that have been done.

Reply Quote
Date: 23/04/2013 16:15:07
From: OCDC
ID: 299780
Subject: re: GABA receptors

Hey purps, without elaborating, is the original problem something I already know about, or something new?

Is the doxy helping you sleep at all?

Reply Quote
Date: 23/04/2013 16:18:16
From: purple
ID: 299782
Subject: re: GABA receptors

I’m just reading some clinical trials and I’m a bit afraid.
it’s compared to valium quite a bit and I do not want anything that can possibly mess with my brain.
I know the dozile can be addictive, so I’m taking less and less.
feeling a bit lost

Reply Quote
Date: 23/04/2013 16:18:58
From: purple
ID: 299783
Subject: re: GABA receptors

who are you OCDC?

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Date: 23/04/2013 16:19:06
From: OCDC
ID: 299784
Subject: re: GABA receptors

Alex

Reply Quote
Date: 23/04/2013 16:21:16
From: purple
ID: 299785
Subject: re: GABA receptors

Jolly good. this is something different.
email me your address pls
(boringhousewife, optushome)

Reply Quote
Date: 23/04/2013 16:23:04
From: poikilotherm
ID: 299786
Subject: re: GABA receptors

purple said:


I’m just reading some clinical trials and I’m a bit afraid.
it’s compared to valium quite a bit and I do not want anything that can possibly mess with my brain.
I know the dozile can be addictive, so I’m taking less and less.
feeling a bit lost

At worst dozile becomes ineffective when taken in excess or for prolonged periods. Addiction is mostly/all psychological in this case.

Reply Quote
Date: 23/04/2013 16:27:59
From: OCDC
ID: 299789
Subject: re: GABA receptors

Sent.

Reply Quote
Date: 23/04/2013 17:18:43
From: purple
ID: 299830
Subject: re: GABA receptors

Yeah, the pharmacist told me about that poik.
I’ve had some bad experiences with withdrawal from prescription drugs, so I’m being really careful.

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