Date: 1/01/2014 23:34:43
From: morrie
ID: 462510
Subject: Hairy root cultures for vaccine production

It appears that hairy root cultures might herald a new generation of vaccines.

“Hairy root cultures, generated from edible plants and producing target antigens, provide a potential approach for the development of vaccines for oral delivery. With this approach, there are no protein extraction and purification costs and the active biomolecule is protected by the plant cell wall during passage through the upper gastrointestinal tract. This allows for gradual release of antigen at mucosal surfaces in the gut. Lyophilized hairy root cultures expressing vaccine antigens can be stored at ambient temperature for extended periods of time, which should facilitate storage and distribution, ultimately allowing for large populations to be vaccinated”

http://www.ncbi.nlm.nih.gov/pubmed/23649385

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Date: 1/01/2014 23:48:14
From: Rule 303
ID: 462517
Subject: re: Hairy root cultures for vaccine production

It’s a hell of an interesting idea, Morrie, but as an intellectual exercise, all I’m seeing is multiple points of failure. Have you got more info about this methods of dosing (than the Abstract)?

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Date: 1/01/2014 23:50:43
From: Rule 303
ID: 462519
Subject: re: Hairy root cultures for vaccine production

method, not methods.

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Date: 1/01/2014 23:54:35
From: morrie
ID: 462520
Subject: re: Hairy root cultures for vaccine production

Rule 303 said:


It’s a hell of an interesting idea, Morrie, but as an intellectual exercise, all I’m seeing is multiple points of failure. Have you got more info about this methods of dosing (than the Abstract)?

Not really, Rule. There is quite a lot of current interest in hairy root culture for all sorts of things. I just happened on the topic and was browsing a few articles. Biology is not my field, but it does sort of overlap with chemical engineering.

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Date: 1/01/2014 23:58:19
From: ChrispenEvan
ID: 462522
Subject: re: Hairy root cultures for vaccine production

i’m sure i have heard about this recently. seems to rings a bell. dunno where though.

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Date: 2/01/2014 09:21:52
From: The Rev Dodgson
ID: 462587
Subject: re: Hairy root cultures for vaccine production

morrie said:


hairy root cultures

Sounds like my sort of music.

(sorry)

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Date: 2/01/2014 09:22:23
From: roughbarked
ID: 462588
Subject: re: Hairy root cultures for vaccine production

The Rev Dodgson said:


morrie said:

hairy root cultures

Sounds like my sort of music.

(sorry)

I grok.

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