Allergic reaction of Melbourne girl Amelie King sparks debate over school nut ban
So what are the main causes of nut allergies?
Is there any treatment, or line of investigation into a treatment?
dv said:
Allergic reaction of Melbourne girl Amelie King sparks debate over school nut banSo what are the main causes of nut allergies?
Is there any treatment, or line of investigation into a treatment?
FIIK, FIIAK.
Yes.
Nuts and allergies ASICA website
“Children’s allergy specialists at Evelina Children’s Hospital, part of Guys and St. Thomas NHS Foundation Trust are conducting the LEAP Study to determine how to best prevent peanut allegy in children.”
the main cause of nut allergies are nuts
Arts said:
Rule 303 said:
dv said:Nut allergies, eh?I thought most primary schools had a blanket ban on anything that might contain nuts?
it doesn’t matter.. apparently you can give your child peanut butter in the morning for breakfast and they can still affect a child at school.
Which is why the risk control measure (of banning nuts at school) is only one of several put in place. It seems to be a very effective control in its own right, but no control is bomb-proof.
Rule 303 said:
Arts said:
Rule 303 said:I thought most primary schools had a blanket ban on anything that might contain nuts?
it doesn’t matter.. apparently you can give your child peanut butter in the morning for breakfast and they can still affect a child at school.
Which is why the risk control measure (of banning nuts at school) is only one of several put in place. It seems to be a very effective control in its own right, but no control is bomb-proof.
what are some of the other measures?
Arts said:
what are some of the other measures?
There’s always five types:
ABC had some people talking about very slow introduction of nuts for allergic children working, I think it was Friday when I was driving home. And this morning I caught someone saying it is not longer recommended to pregnant women not to eat peanuts.
I have to say I’d not heard of that recommendation during pregnancy (not having been pregnant, I suppose) but it does seem to defy logic. Bodies need contact to develop strategies to deal with stuff. Why would you not do it safely while in the womb?
It’s changed back and forth a few times in my lifetime, buffy, mainly because there is no fantastic evidence in either direction…
I don’t see why people kick up a stink about not being able to take nuts to school. Do they really want a child’s death or life-threatening illness on their conscience? I’d say probably not. Kid can go home and eat a whole jarful if they want after school…
OCDC said:
It’s changed back and forth a few times in my lifetime, buffy, mainly because there is no fantastic evidence in either direction…I don’t see why people kick up a stink about not being able to take nuts to school. Do they really want a child’s death or life-threatening illness on their conscience? I’d say probably not. Kid can go home and eat a whole jarful if they want after school…
first they came for the nuts, and no one spoke
then they came for the vegemite, and they can GAGF!!!
Dropbear said:
OCDC said:
It’s changed back and forth a few times in my lifetime, buffy, mainly because there is no fantastic evidence in either direction…I don’t see why people kick up a stink about not being able to take nuts to school. Do they really want a child’s death or life-threatening illness on their conscience? I’d say probably not. Kid can go home and eat a whole jarful if they want after school…
first they came for the nuts, and no one spoke
then they came for the vegemite, and they can GAGF!!!
stop touching the other kiddies.. kids these days play with their ipads, not each other
I’d imagine the increase in nut allergies is associated with the increase in allergies in general.
Bubblecar said:
I’d imagine the increase in nut allergies is associated with the increase in allergies in general.
probably related to the increased number of nutters around
Dropbear said:
Bubblecar said:
I’d imagine the increase in nut allergies is associated with the increase in allergies in general.
probably related to the increased number of nutters around
I don’t think there has been an increase, just more of them can be heard via the interwebs.
Skunkworks said:
Dropbear said:
Bubblecar said:
I’d imagine the increase in nut allergies is associated with the increase in allergies in general.
probably related to the increased number of nutters around
I don’t think there has been an increase, just more of them can be heard via the interwebs.
yes, the woowoonet is a fearsome and terrible beast
Dropbear said:
Skunkworks said:
Dropbear said:probably related to the increased number of nutters around
I don’t think there has been an increase, just more of them can be heard via the interwebs.
yes, the woowoonet is a fearsome and terrible beast
Chemtrails could be contributing. Or maybe all those UFO anal probings are actually some kind of reproductive technique, and interbreeding with aliens is resulting in more allergies to Earth foods.
ive missed this whole chemtrails thing .. i need to go get some lerning..
>Largely inhabited by tree-huggers and warm & fuzzies.
Don’t know about that. Many woo-wooers are far-right “patriot” types, very distrustful of governments.
Dropbear said:
ive missed this whole chemtrails thing .. i need to go get some lerning..
Bubblecar said:
>Largely inhabited by tree-huggers and warm & fuzzies.Don’t know about that. Many woo-wooers are far-right “patriot” types, very distrustful of governments.
Tamb said:
Dropbear said:
ive missed this whole chemtrails thing .. i need to go get some lerning..
The web is full of chemtrail stuff.
For the web is dark and full of terrors.
Dropbear said:
Tamb said:
Dropbear said:
ive missed this whole chemtrails thing .. i need to go get some lerning..
The web is full of chemtrail stuff.For the web is dark and full of terrors.
Dropbear said:
Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
ive missed this whole chemtrails thing .. i need to go get some lerning..
Michael V said:
Dropbear said:Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
ive missed this whole chemtrails thing .. i need to go get some lerning..
apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
Dropbear said:
Lismore area they are everywhere, along with the “Lock the Gate” and “Say no to coal seam gas” stickers.
Michael V said:
Dropbear said:Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
ive missed this whole chemtrails thing .. i need to go get some lerning..
apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
I’ve not seen those ones (but I have read of them). Not too many bumper stickers around here. Maybe the people of African descent (of which there are plenty in the neighbourhood) don’t use those stickers.
Dropbear said:
Michael V said:
Dropbear said:Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
ive missed this whole chemtrails thing .. i need to go get some lerning..
apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
Out A Town way
So I’m gonna turn around with a great smile
And walk my white ass back across 8 Mile
Dropbear said:
Michael V said:
Dropbear said:Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
ive missed this whole chemtrails thing .. i need to go get some lerning..
apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
I saw one on a car that had all sorts of New Zealand stickers on it. It said – “too late, we’re here”.
Michael V said:
Dropbear said:Lismore area they are everywhere, along with the “Lock the Gate” and “Say no to coal seam gas” stickers.
Michael V said:
Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
I’ve not seen those ones (but I have read of them). Not too many bumper stickers around here. Maybe the people of African descent (of which there are plenty in the neighbourhood) don’t use those stickers.
There are also “my family” stick figure bumper stickers which were all so fashionable for 5 minutes back in 2000something
party_pants said:
Dropbear said:
Michael V said:
Haven’t you seen the hippy car stickers? “Say No to Chemtrails – stop the government poisoning us all.”
apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
I saw one on a car that had all sorts of New Zealand stickers on it. It said – “too late, we’re here”.
lmao gold.
Dropbear said:
I completely and utterly hate those things. They make my blood boil. And they are seemingly everywhere…
Michael V said:
Dropbear said:Lismore area they are everywhere, along with the “Lock the Gate” and “Say no to coal seam gas” stickers.apparently not …
most bumper stickers around here seem to be ‘fuck off we’re full” or “if you don’t love it, leave”…
I’ve not seen those ones (but I have read of them). Not too many bumper stickers around here. Maybe the people of African descent (of which there are plenty in the neighbourhood) don’t use those stickers.
There are also “my family” stick figure bumper stickers which were all so fashionable for 5 minutes back in 2000something
Michael V said:
Dropbear said:I completely and utterly hate those things. They make my blood boil. And they are seemingly everywhere…
Michael V said:
Lismore area they are everywhere, along with the “Lock the Gate” and “Say no to coal seam gas” stickers.I’ve not seen those ones (but I have read of them). Not too many bumper stickers around here. Maybe the people of African descent (of which there are plenty in the neighbourhood) don’t use those stickers.
There are also “my family” stick figure bumper stickers which were all so fashionable for 5 minutes back in 2000something
xkcd #946
published 2 September 2011
Family Decals
Transcript
{Two cars are parked next to each other. The car on the left is an urban SUV and has stickers on the rear window representing a family. From left to right there is an adult male, adult female, female youth, male youth, and young child. The car on the right is a sporty hatch back, it has similar stickers on the rear window, with an adult male and adult female. Instead of the youth and child stickers there is instead a large pile of money.}
Sorry. That was supposed to go into Chat.
Rule 303 said:
Arts said:what are some of the other measures?There’s always five types:
- Elimination – Ban all nuts & nut products at school.
- Substitution – Introduce other foods that include the same nutrients.
- Engineering – Modify the nuts to remove the allergen compounds.
- Administration – Educate the kids not to share food, wash hands, put up reminder signs, train the staff, have Adrenaline auto-injectors available, have an ‘Illness Action Plan’ for kids who are know to be allergic.
- Personal protective equipment – Not really appropriate in the example, but a severely allergic kid might have to wear protective gear to prevent exposure.
none of those address the problem of a kid eating peanut butter on their toast and then going to school. mmaybe washing the hands and don’t touch other kids.. but from what I have read it could be just ‘smelling’ a peanut can have an affect.
I’dstill go for number three… what are the kids that can eat nuts going to miss nutritionally if we ban nuts everywhere?
buffy said:
ABC had some people talking about very slow introduction of nuts for allergic children working, I think it was Friday when I was driving home. And this morning I caught someone saying it is not longer recommended to pregnant women not to eat peanuts.
I have to say I’d not heard of that recommendation during pregnancy (not having been pregnant, I suppose) but it does seem to defy logic. Bodies need contact to develop strategies to deal with stuff. Why would you not do it safely while in the womb?
I was told this when I was pregnant with the second, but not the first (so 6 years ago, but not 8)
I asked some friends who are Indian.. about this and while breastfeeding.. and their response was that they don’t modify their diet… and the Indians certainly aren’t lacking in population.
Arts said:
Rule 303 said:
Arts said:what are some of the other measures?There’s always five types:
- Elimination – Ban all nuts & nut products at school.
- Substitution – Introduce other foods that include the same nutrients.
- Engineering – Modify the nuts to remove the allergen compounds.
- Administration – Educate the kids not to share food, wash hands, put up reminder signs, train the staff, have Adrenaline auto-injectors available, have an ‘Illness Action Plan’ for kids who are know to be allergic.
- Personal protective equipment – Not really appropriate in the example, but a severely allergic kid might have to wear protective gear to prevent exposure.
none of those address the problem of a kid eating peanut butter on their toast and then going to school. mmaybe washing the hands and don’t touch other kids.. but from what I have read it could be just ‘smelling’ a peanut can have an affect.
I’dstill go for number three… what are the kids that can eat nuts going to miss nutritionally if we ban nuts everywhere?
It’s more than nutrition. Kids like peanuts.
If it were just nutrition they’d be given broccoli for lunch.
Michael V said:
Dropbear said:I completely and utterly hate those things. They make my blood boil. And they are seemingly everywhere…
Michael V said:
Lismore area they are everywhere, along with the “Lock the Gate” and “Say no to coal seam gas” stickers.I’ve not seen those ones (but I have read of them). Not too many bumper stickers around here. Maybe the people of African descent (of which there are plenty in the neighbourhood) don’t use those stickers.
There are also “my family” stick figure bumper stickers which were all so fashionable for 5 minutes back in 2000something
yeah I dislike them too… all these people who go on about protecting their privacy then advertise for all to see their family dynamics
My daughter’s primary school has a blanket ban on nuts. She went back to school last Wednesday and SWMBO packed some almonds into her lunch box. Miss 10 got home that evening, rolled her eyes, and explained to SWMBO that she opened up her lunch box, saw the nuts, and put them away. She then did another roll of the eyes
OCDC said:
It’s changed back and forth a few times in my lifetime, buffy, mainly because there is no fantastic evidence in either direction…I don’t see why people kick up a stink about not being able to take nuts to school. Do they really want a child’s death or life-threatening illness on their conscience? I’d say probably not. Kid can go home and eat a whole jarful if they want after school…
the reason it’s a ‘deal’ is because you can’t buy anything that doesn’t have the warning ‘may contain traces of nut” which means that all snacks need to be made at home.. which is fine for the supermums and the ones who don;t work.. but not everyone is a wizz in the kitchen and not every mother has the time to be cooking slices.
I actually made a carrot cake for my kids once.. no nuts at all, but my daughter was still told she couldn’t eat it at school because the recipe has nuts in it (it didn’t seem to matter that I deliberately made the cake without nuts for them to take to school… it upset her)
as much as I’d hate for a kiddie to die from this.. I wouldn’t blame myself for giving my kids something at home and it transferring to school. (apart from the fact that privacy issues mean we aren’t told which kids have allergies and which don’t.. so you can’t even say – hey, don’t go near little johnny today since you’ve had peanut butter for breakfast)
What are the main allergenic compounds in tree nuts?
UpToDate:
Nine major and minor allergenic proteins in peanut (Arachis hypogaea), designated Ara h 1-9, have been identified that are responsible for IgE-mediated reactions . The dominant allergens in most populations are Ara h 1-3, which are vicilin, conglutin, and glycinin seed storage proteins, respectively. Ara h 4, 6 and 7 are also seed storage proteins. Ara h 4 is a nearly identical isoform of Ara h 3. Ara h 6 is highly homologous to Ara h 2, and Ara h 7 is also a conglutin.
Ara h 5, 8, and 9 are proteins that are associated with pollen-food allergy syndrome (oral allergy syndrome). Ara h 5 is a profilin, Ara h 8 is a Bet v 1 (a birch allergen) homologue , and Ara h 9 is a nonspecific lipid transfer protein similar to Pru p 3 (a peach allergen) . (See “Pathogenesis of oral allergy syndrome (pollen-food allergy syndrome)”, section on ‘Allergens in PFAS’.)
In the United States and United Kingdom populations, more than 90 percent of patients with peanut allergy have specific IgE to Ara h 1 and 2, and 45 to 95 percent have specific IgE to Ara h 3 . In contrast, specific IgE to Ara h 8 or 9 is more common in individuals with concomitant birch pollen or peach sensitization, especially in northern and southern Europe, respectively . The presence of IgE antibodies to Ara h 2 is most closely associated with clinical reactivity to peanut .
Tree nut and seed allergens are less well characterized than peanut allergens, although a number of tree nut and seed allergens have been identified . These allergens include pollen allergen homologues, such as Bet v 1-like proteins and profilins, and more stable allergens, such as seed storage proteins and some lipid transfer proteins. Issues of cross-reactivity between allergens are discussed in greater detail separately. (See “Food allergens: Overview of clinical features and cross-reactivity” and ‘Allergies to other foods’ below.)
Allergy to peanut, tree nuts, and seeds can develop through primary sensitization to the food itself or through secondary sensitization via sensitization to cross-reactive allergens (eg, birch pollen). (See “Pathogenesis of food allergy”, section on ‘Routes of allergen sensitization’ and “Pathogenesis of oral allergy syndrome (pollen-food allergy syndrome)”.)
Several reasons have been proposed to explain why peanut (and possibly tree nuts and seeds) are more allergenic than other foods:
■Seed storage proteins contain disulfide bonds that give these proteins high thermostability and resistance to extreme pH values. In addition, these proteins are often glycosylated, which further increases thermal and proteolytic stability. Ara h 1 in the glycosylated form can act as a Th2 adjuvant, activating dendritic cells to induce maturation and proliferation of Th2 cells, which promote IgE production . (See “Molecular features of food allergens”.)
■Certain factors involved in harvesting and processing may also make these foods more allergenic. A greater amount of Ara h 1 is found in larger, more mature peanut kernels and in peanuts dried or cured at higher temperatures . High heat roasting leads to glycation reactions that increase protein stability and allergenicity.
■Metabolized vegetable oils, such as peanut oil can serve as adjuvants, increasing the immune response to antigens . Whipping or emulsifying peanut butter to prevent the oil from separating from the peanut solids brings more of the water-soluble protein into direct contact with the oil, potentially increasing the immunogenicity of peanut proteins ingested in this manner. (See “Molecular features of food allergens”.)
so is it possible to alter nuts to grow without these proteins?
Arts said:
so is it possible to alter nuts to grow without these proteins?
Flavour, cost, growability etc might all change. And it might not taste like a peanut in which case you might as well have cashews.
And to answer earlier questions:
Maternal ingestion of food allergens — An association between maternal ingestion of food allergens during pregnancy and lactation and the development of food allergies in offspring was suggested , although whether there is a causal relationship is debated. One subsequent study noted that allergen-specific IgE in cord blood was maternal in origin and IgE specific for the same foods was not found in infant blood at six months of age . Furthermore, findings from a murine model of peanut allergy suggest that ingestion of a low dose of peanut, compared to no peanut, during pregnancy and lactation lowers the risk of peanut allergy in the offspring . In addition, some hypothesize that sensitization occurs as a result of environmental exposure (eg, skin contact) as opposed to ingestion exposure, and the level of maternal consumption of peanut may rather be a marker for the level of environmental exposure in the household . In a large cohort of infants at high risk for developing peanut allergy, a direct correlation was found between the amount of peanut ingested by the mother during pregnancy and the level of peanut-specific IgE in the offspring . However, whether this reflects clinical reactivity to peanut remains to be determined. (See “Primary prevention of allergic disease: Maternal avoidance diets in pregnancy and lactation”.)