When severely burned, why does the skin come away; what process is involved in the separation of skin and flesh?

Divine Angel said:

When severely burned, why does the skin come away; what process is involved in the separation of skin and flesh?

Necrosis..

“…necrosis often affects sheets of cells within a tissue. This is due to the deleterious effects that necrotic cells have on surrounding cells. Necrotic cells are characterized by the loss of membrane integrity, organelle swelling, and lysosomal leakage. The cellular DNA also non-specifically degrades into a variety of molecular base sizes. Another distinct feature of necrosis is a significant inflammatory response. The release of cellular material into the extracellular fluid mobilizes inflammatory cells to release chemotactic agents and remove the necrotic cells.”

Ah, I didn’t factor the inflammatory response.

My sister gave me a book about deaths in Yellowstone Park. The first chapter is people who have fallen/dived/bathed into the hot springs. The average temps of those springs range 66C-98C.

The voices tell me to burn things

Divine Angel said:

Ah, I didn’t factor the inflammatory response.

My sister gave me a book about deaths in Yellowstone Park. The first chapter is people who have fallen/dived/bathed into the hot springs. The average temps of those springs range 66C-98C.

‘orrid ways to die in a National Park.

What fucking inflammatory response you arseclown

Dropbear said:

What fucking inflammatory response you arseclown

That’s a fairly inflammatory response!

Dropbear said:

The voices tell me to burn things

Don’t act on what “the voices” tell you. Feel free to listen to the voices, but don’t fear them and don’t act on what they tell you. I know a few more mental tricks to deal with them, but here is not the place.

Leakage of fluids from damaged cells cause sloughing of skin. I’m not a medical person, but suspect that the layer of subsurface skin called “stratum spinosum” contains cells with a much higher percentage of water than those closer to the surface, so that is the under-layer of skin that gives way in serious burns.