People with schizophrenia and some who use cannabis may have certain genes in common, according to new research.
The findings may partly explain the following, long-established link between cannabis use and psychotic disorders: The rate of people who smoke pot is higher among those who are diagnosed with schizophrenia than it is in the general population. In addition, studies have shown that using cannabis can lead to psychotic episodes or worsen a person’s existing symptoms, which suggests that the substance could trigger the psychotic disorder.
But the new results suggest that part of the association between the two might actually be due to both of them being linked with the same genes, said Robert Power, a researcher at the Institute of Psychiatry at King’s College London.
“To some extent, those genes that we have identified as being ‘schizophrenia-inducing’ are also genes that can contribute to cannabis use,” Power said.
Power and his colleagues looked at the pot-smoking habits of 2,082 healthy people as well as their genetic profiles, focusing on the genes that have been identified as related to schizophrenia.
The results showed that people who had genes linked with schizophrenia were also more likely to use cannabis, and use it more frequently, compared with people who didn’t have the schizophrenia-risk genes, according to the study, published today (June 24) in the journal Molecular Psychiatry.
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