http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0107541#s4

Prediction of mortality has focused on disease and frailty, although antecedent biomarkers may herald broad physiological decline. Olfaction, an ancestral chemical system, is a strong candidate biomarker because it is linked to diverse physiological processes. We sought to determine if olfactory dysfunction is a harbinger of 5-year mortality in the National Social Life, Health and Aging Project , a nationally representative sample of older U.S. adults. 3,005 community-dwelling adults aged 57–85 were studied in 2005–6 (Wave 1) and their mortality determined in 2010–11 (Wave 2).

poikilotherm said:

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0107541#s4

Prediction of mortality has focused on disease and frailty, although antecedent biomarkers may herald broad physiological decline. Olfaction, an ancestral chemical system, is a strong candidate biomarker because it is linked to diverse physiological processes. We sought to determine if olfactory dysfunction is a harbinger of 5-year mortality in the National Social Life, Health and Aging Project , a nationally representative sample of older U.S. adults. 3,005 community-dwelling adults aged 57–85 were studied in 2005–6 (Wave 1) and their mortality determined in 2010–11 (Wave 2).

Are they linking it to a precursor to a decline in health or the inability to smell could increase the odds of you dying from something related to needing the ability to smell.

Of course, loss of the sense of smell is a marker for brain tumour.

buffy said:

Of course, loss of the sense of smell is a marker for brain tumour.

And yet, it doesn’t predict death from cancer, strange eh.

Cymek said:

poikilotherm said:

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0107541#s4

Prediction of mortality has focused on disease and frailty, although antecedent biomarkers may herald broad physiological decline. Olfaction, an ancestral chemical system, is a strong candidate biomarker because it is linked to diverse physiological processes. We sought to determine if olfactory dysfunction is a harbinger of 5-year mortality in the National Social Life, Health and Aging Project , a nationally representative sample of older U.S. adults. 3,005 community-dwelling adults aged 57–85 were studied in 2005–6 (Wave 1) and their mortality determined in 2010–11 (Wave 2).

Are they linking it to a precursor to a decline in health or the inability to smell could increase the odds of you dying from something related to needing the ability to smell.

They only looked at mortality (not ‘decline in health’), so, it’s just risk of being dead over a 5 year period. Your odds of dying go up in that 5 years if you’ve lost the sense of smell and are aged betweem 57-85.

buffy said:

Of course, loss of the sense of smell is a marker for brain tumour.

And the common cold.

Diseases causing sensory changes were accounted for.

where sensory = changes in smell

I lost all sense of smell about 5 maybe 6 years ago

wookiemeister said:

I lost all sense of smell about 5 maybe 6 years ago

Wookie, wookie, wookie, wookie, WHY WON’T YOU ANSWER!!

Cymek said:

wookiemeister said:

I lost all sense of smell about 5 maybe 6 years ago

Wookie, wookie, wookie, wookie, WHY WON’T YOU ANSWER!!

hEl4P

i’ll tell the missus to drop me off at the tip, they are having a free clean up weekend so it won’t cost her a cent if something untoward happens to me

wookiemeister said:

i’ll tell the missus to drop me off at the tip, they are having a free clean up weekend so it won’t cost her a cent if something untoward happens to me

I think they charge extra for horse carcasses.

one of the few parts of the brain that grows new brain cells?…..so if smell decline corresponded with loss of cell turnover (a different thing I know) elsewhere throughout the body, sort of the end of your DNA replicating…..

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Umm… I think there is a minimum requirement before a wake is to take place. Just saying.

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Are you putting aside money for flight and accommodation for the Holiday forum regulars? I prefer to stay in 5 star places, BTW.

Oh, and free grog, there must be free grog.

sibeen said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Are you putting aside money for flight and accommodation for the Holiday forum regulars? I prefer to stay in 5 star places, BTW.

Oh, and free grog, there must be free grog.

Yes, and hot cherrios with a toothpick stuck in them and a dipping bowl of tomato sauce.

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Morris Dancing and giggling.

Billzilla has no sense of smell. He is doomed.

Peak Warming Man said:

sibeen said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Are you putting aside money for flight and accommodation for the Holiday forum regulars? I prefer to stay in 5 star places, BTW.

Oh, and free grog, there must be free grog.

Yes, and hot cherrios with a toothpick stuck in them and a dipping bowl of tomato sauce.

Jaysus, PWM, he’s not going to go all out on this. Pull your head in, man.

So did they go to a shed load of old peoples homes and do a smell test on the patients and then come back in 12 months to see who’s fallen off the perch?

ms spock said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Morris Dancing and giggling.

Billzilla has no sense of smell. He is doomed.

Or blessed

>>Billzilla has no sense of smell. He is doomed.

He’ll be fine, the last thing to go is your sense of humour and his is still well active.

sibeen said:

Peak Warming Man said:

sibeen said:

Are you putting aside money for flight and accommodation for the Holiday forum regulars? I prefer to stay in 5 star places, BTW.

Oh, and free grog, there must be free grog.

Yes, and hot cherrios with a toothpick stuck in them and a dipping bowl of tomato sauce.

Jaysus, PWM, he’s not going to go all out on this. Pull your head in, man.

But fairy bread is a must.

If I get bad news I would rent the town hall, a few grands worth of free piss and a big order from the pizza shop for a living wake.

OCDC said:

sibeen said:

Peak Warming Man said:

Yes, and hot cherrios with a toothpick stuck in them and a dipping bowl of tomato sauce.

Jaysus, PWM, he’s not going to go all out on this. Pull your head in, man.

But fairy bread is a must.

+1

OCDC said:

sibeen said:

Peak Warming Man said:

Yes, and hot cherrios with a toothpick stuck in them and a dipping bowl of tomato sauce.

Jaysus, PWM, he’s not going to go all out on this. Pull your head in, man.

But fairy bread is a must.

Shush……….you’ll wake Bubblecar up.

Peak Warming Man said:

OCDC said:

sibeen said:

Jaysus, PWM, he’s not going to go all out on this. Pull your head in, man.

But fairy bread is a must.

Shush……….you’ll wake Bubblecar up.

He’ll be up soon to start the spit anyway. Nearly suppertime.

Woohoo 4 day weekend

Dropbear said:

Woohoo 4 day weekend

When you cant smell victory you’ll be dead soon.

ratty one said:

ms spock said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Morris Dancing and giggling.

Billzilla has no sense of smell. He is doomed.

Or blessed

Or bananerish.

Peak Warming Man said:

>>Billzilla has no sense of smell. He is doomed.

He’ll be fine, the last thing to go is your sense of humour and his is still well active.

He is a crazy banana.

Dropbear said:

Woohoo 4 day weekend

5 days here!

Winning is finishing the week with a negative balance on your public transport card.

:-)

ms spock said:

OCDC said:

sibeen said:

Jaysus, PWM, he’s not going to go all out on this. Pull your head in, man.

But fairy bread is a must.

+1

And chocolate crackles.

buffy said:

ms spock said:

OCDC said:

But fairy bread is a must.

+1

And chocolate crackles.

I’m more a Honey Joys man myself

For god’s sake, there is only so much lucre that can be spread around. We have to account for flights, accommodation and booze. We cannot be spending Mr V’s hard earned’s on frivolous items. You lot are just going to have to lower your standards and have some respect. Bring your own fairy bread, chocolate crackles etc, if you must consider them a must.

sibeen said:

For god’s sake, there is only so much lucre that can be spread around. We have to account for flights, accommodation and booze. We cannot be spending Mr V’s hard earned’s on frivolous items. You lot are just going to have to lower your standards and have some respect. Bring your own fairy bread, chocolate crackles etc, if you must consider them a must.

It’ll be BYO to reduce costs…

ratty one said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Umm… I think there is a minimum requirement before a wake is to take place. Just saying.

Poik’s article reckons I’ll be dead soon…

sibeen said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

Are you putting aside money for flight and accommodation for the Holiday forum regulars? I prefer to stay in 5 star places, BTW.

Oh, and free grog, there must be free grog.

Heh!

AwesomeO said:

If I get bad news I would rent the town hall, a few grands worth of free piss and a big order from the pizza shop for a living wake.

I like this notion.

:)

If it is any consolation, we will all be dead soon.

dv said:

If it is any consolation, we will all be dead soon.

No matter, it will still be a while before I drop off the perch. I can still smell things, at least. Usually myself.

If it is any consolation, we will all be dead soon.

possibly trauma and long-term stress can reduce olfactory sensitivity, but the article is talking of some decline associated with old age, still this wouldn’t exclude trauma and stress in old age….

dv said:

If it is any consolation, we will all be dead soon.

You keep saying that, one day it’ll be true.

dv said:

If it is any consolation, we will all be dead soon.

whilst true, it is no consolation.

dv said:

If it is any consolation, we will all be dead soon.

On my before last trip to hospital and on oxygen I thought I was close. But it didn’t actually make me think of regrets and such as the cliche goes, I was just focused on breathing.

sibeen said:

For god’s sake, there is only so much lucre that can be spread around. We have to account for flights, accommodation and booze. We cannot be spending Mr V’s hard earned’s on frivolous items. You lot are just going to have to lower your standards and have some respect. Bring your own fairy bread, chocolate crackles etc, if you must consider them a must.

:)

transition said:

possibly trauma and long-term stress can reduce olfactory sensitivity, but the article is talking of some decline associated with old age, still this wouldn’t exclude trauma and stress in old age….

There exists a person whom I know well, who drinks a bit at least one night a week. By a bit I do mean until he’s gone awol. He was given a taxi ride by some bloke he met in the local watering hole and obviously didn’t pay much attention to that until the bloke came inside with him. When the other bloke wanted him to crash out so he could steal everything in the place my mate came to his senses and said no. The thief tried to king hit him and got him on the third eye. Though my mate smashed the shyte out of the would be thief and had him scuttling for exits to save his life, he still to this day cannot smell anything.

Michael V said:

sibeen said:

For god’s sake, there is only so much lucre that can be spread around. We have to account for flights, accommodation and booze. We cannot be spending Mr V’s hard earned’s on frivolous items. You lot are just going to have to lower your standards and have some respect. Bring your own fairy bread, chocolate crackles etc, if you must consider them a must.

:)

I’ve just been up Wilson’s Creek .. took a paddle in a bag of custard apples, a bag of avo’s and a dozen organic free range eggs but it seemed I needed to do more. Had to fix a screen window that hadn’t been repaired or in place in years. Did that and drove home in the dark in totally unfamiliar territory. The purpose of the journey? To see fireflies and to chat to someone whom found me on the internet.

buffy said:

ms spock said:

OCDC said:

But fairy bread is a must.

+1

And chocolate crackles.

+1

>Though my mate smashed the shyte out of the would be thief and had him scuttling for exits to save his life, he still to this day cannot smell anything

Lived nextdoor to a guy that got assaulted badly (lived in the wrong end of town at one time I did), crack over the head, had no sense of smell or olfactory capacity at all as consequence. Remember him well, first person I ever met that apparently had zero fear of spiders, sort of played with them and stroked them.

Witty Rejoinder said:

buffy said:

ms spock said:

+1

And chocolate crackles.

I’m more a Honey Joys man myself

-1

ms spock said:

Witty Rejoinder said:

buffy said:

And chocolate crackles.

I’m more a Honey Joys man myself

I’m happy with a grapefruit juice from my own tree.
-1

AwesomeO said:

dv said:

If it is any consolation, we will all be dead soon.

On my before last trip to hospital and on oxygen I thought I was close. But it didn’t actually make me think of regrets and such as the cliche goes, I was just focused on breathing.

Breathing is good.

AwesomeO said:

dv said:

If it is any consolation, we will all be dead soon.

On my before last trip to hospital and on oxygen I thought I was close. But it didn’t actually make me think of regrets and such as the cliche goes, I was just focused on breathing.

Do you have a portable oxygen source of any kind?

morrie said:

AwesomeO said:

dv said:

If it is any consolation, we will all be dead soon.

On my before last trip to hospital and on oxygen I thought I was close. But it didn’t actually make me think of regrets and such as the cliche goes, I was just focused on breathing.

Do you have a portable oxygen source of any kind?

Not needed, i just left things too late, slowed down too much and by the time I got to hospital my lungs were white and full of crap. No surfaces for oxygen transfer.

AwesomeO said:

morrie said:

AwesomeO said:

On my before last trip to hospital and on oxygen I thought I was close. But it didn’t actually make me think of regrets and such as the cliche goes, I was just focused on breathing.

Do you have a portable oxygen source of any kind?

Not needed, i just left things too late, slowed down too much and by the time I got to hospital my lungs were white and full of crap. No surfaces for oxygen transfer.

so what did they do to get rid of it?

wookiemeister said:

AwesomeO said:

morrie said:

Do you have a portable oxygen source of any kind?

Not needed, i just left things too late, slowed down too much and by the time I got to hospital my lungs were white and full of crap. No surfaces for oxygen transfer.

so what did they do to get rid of it?

Wire brush and dettol.

AwesomeO said:

morrie said:

AwesomeO said:

On my before last trip to hospital and on oxygen I thought I was close. But it didn’t actually make me think of regrets and such as the cliche goes, I was just focused on breathing.

Do you have a portable oxygen source of any kind?

Not needed, i just left things too late, slowed down too much and by the time I got to hospital my lungs were white and full of crap. No surfaces for oxygen transfer.

OK. I happened to be reading about them the other day. Seems that portable units that provide around 27% oxygen from air are in common use for people with lung issues.

peppermint vapour might help you AO

peppermint vapour might help you AO

wookiemeister said:

AwesomeO said:

morrie said:

Do you have a portable oxygen source of any kind?

Not needed, i just left things too late, slowed down too much and by the time I got to hospital my lungs were white and full of crap. No surfaces for oxygen transfer.

so what did they do to get rid of it?

Antibiotics and physio. At the moment my lungs are fine, I can breath easily and can walk a km or so with ease so don’t require oxygen.

wookiemeister said:

peppermint vapour might help you AO

Or better yet, professional doctors and not random people on internet forums.

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

We haven’t even had a proper memorial for Geoff D yet. Wait your turn.

Divine Angel said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

We haven’t even had a proper memorial for Geoff D yet. Wait your turn.

Michael V has no nose
How does he smell?
Terrible

Divine Angel said:

Michael V said:

Oh, shit. My sense of smell has been going away quite fast in the last few months. Seriously. I used to have a great sense of smell, Mrs V a poor one. Just recently it seems she can now smell lots of things I no longer notice, where I formerly would have.

Make sure I get a tops wake, please.

We haven’t even had a proper memorial for Geoff D yet. Wait your turn.

Yeah.

I printed out some photos of him at that pud at Michael V’s house. Seems like such a long time ago.