Most of the material in the solar system underwent a period of isotopic homogenisation in the early days.
Although there will be some differences in the isotopic balance of material sourced from different places on earth, or for that matter from most off earth sources such as meteorites known to come from Mars, but the variations are small, typically less than a percent.
However there exists a small amount of material whose isotopic composition is so very different that it has clearly not undergone the early solar system homogenisation: it has retained the isotopic “fingerprint” of an earlier star.
The minerals are usually stable oxides, carbides and nitrides with high-melting points, and may contain inclusions of inert gases.
These specks are mainly recovered from meteorites. They tell a story about their parent stars, and provide information about stellar evolution generally.