Off switch’ for pain discovered: Activating the adenosine A3 receptor subtype is key to powerful pain relief

In research published in the medical journal Brain, Saint Louis University researcher Daniela Salvemini, Ph.D. and colleagues within SLU, the National Institutes of Health (NIH) and other academic institutions have discovered a way to block a pain pathway in animal models of chronic neuropathic pain including pain caused by chemotherapeutic agents and bone cancer pain suggesting a promising new approach to pain relief.

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Hmm, an alternative to opiates, sounds good.

> MRS5698

Chemical 9 from Table 1 of http://www.sciencedirect.com/science/article/pii/S2001037014000415

Based on adenosine (adenine + ribose) with two extra rings, a triple bond, and some halogens added.