Botox is used in the correction of club foot. It is used to relax leg muscles/tendons followed by casting of the foot. This may be preferable to surgical techniques.

https://clinicaltrials.gov/ct2/show/NCT00474032

That looks like it’s the recruiting stuff, the trial hasn’t actually happened yet?

buffy said:

That looks like it’s the recruiting stuff, the trial hasn’t actually happened yet?

As the intro says

This is not a hypothesis-generating study as we are reporting on outcomes of patients who have been treated by this method of clubfoot treatment.

But I don’t think they have actually published the results yet. I think that is just the recruiting phase. I’ll see if I can find a published paper.

They don’t seem to have reported yet:

https://clinicaltrials.gov/ct2/show/results/NCT00474032

Results tab from your link.

Expected finish date is 2023:

https://clinicaltrials.gov/ct2/show/record/NCT00474032

There seems to be an early paper, but the study is not finished:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340848/

Well that was the original paper eight years ago, things have ticked on since then and it appears to have become a standard option.

clubfootclub.org/about/treatment-options/
How is Clubfoot Corrected? – The Clubfoot Club

www​.ncbi.nlm.nih.gov/pubmed/25609054
Early ultrasonographic evaluation of idiopathic clubfeet treated with manipulations, casts, and Botox(®): a double-blind randomized control trial.

That is the paper I linked to. It’s an early results paper. I guess they now have to wait to see if the results hold or not.

It does seem to be just publishing the early results now:

http://link.springer.com/article/10.1007%2Fs11832-015-0633-4

So it’s not a general use treatment yet?

Hang on…which is the interesting bit here? The clubfoot use or that botulinum toxin isn’t only used cosmetically? It’s been used medically for a rather long time now:

http://www.clinicaladvisor.com/botulinum-toxin-treats-a-wide-array-of-medical-conditions/article/305431/

I had a patient back in the 1980s who had essential blepharospasm. That meant he blinked uncontrollably, all the time. His job involved face to face with people. At the time there was a trial in Melbourne of botox to control this condition and he became part of it. It turned out to be a very useful thing. It is also used for other muscle spasm conditions. It’s only rather recently that the public in general became aware of it and it got used cosmetically and in some cases rather indiscriminately.

Used for migraines, post stroke issues and many more…

Clubfoot has been non-surgically treated for years now. Serial casting, with the foot in a slightly more normal position each time, works really well and completely avoids the need for surgery in most.

Could botox be useful in treating cerebral palsy?

Divine Angel said:

Could botox be useful in treating cerebral palsy?

It’s used for fixed flexion deformities and spasticity, but doesn’t fix the initial problem.