How the Body’s Trillions of Clocks Keep Time

Cellular clocks are almost everywhere. Clues to how they work are coming from the places that they’re not.

Cellular clocks are almost everywhere. Clues to how they work are coming from the places that they’re not.
Carrie Partch was at the tail end of her postdoc when she made the first discovery. The structural biologist was looking at a database of human proteins, noting those that shared a piece with the ones she’d been studying. “I was just sort of flipping through it thinking, ‘I should know all of these,’” she recalls. “Then this one came up, and it had a different domain architecture than I’d ever seen.” She looked further into the protein, called PASD1, whose function was unknown. She found that among the few proteins it resembled was one called CLOCK. And that made her sit up straighter — because CLOCK is at the heart of a very large, mysterious process.

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speaking of clocks, I need sleep.

https://www.youtube.com/watch?v=JwYX52BP2Sk

i’d expect day/night cycles have contributed to the structuring (abiogenesis, and evolution) of organic life, that day/night thermal energy cycles incrementally embed information (transformed I suppose), that it is a structuring energy (has potentials), the cyclic thermal gradients, the spectral shifts, and direction changes.

Add a massive random events generator and the right chemistry, and a hydrological cycle, probably gives you an engine of sorts