Date: 5/11/2015 08:11:11
From: mollwollfumble
ID: 797291
Subject: Nicotine?

What do you know about nicotine?

How does it survive being burnt?
Why doesn’t its effectiveness drop off with time?
Why do I never hear of anyone dying from a nicotine overdose?
Why isn’t it sold as an illegal drug?
Are all the good effects of smoking due to nicotine?
What type of drug is it? analgesic? muscle relaxant? antidepressant?

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Date: 5/11/2015 08:17:04
From: roughbarked
ID: 797292
Subject: re: Nicotine?

mollwollfumble said:


What do you know about nicotine?

How does it survive being burnt?
Why doesn’t its effectiveness drop off with time?
Why do I never hear of anyone dying from a nicotine overdose?
Why isn’t it sold as an illegal drug?
Are all the good effects of smoking due to nicotine?
What type of drug is it? analgesic? muscle relaxant? antidepressant?

They are all good questions. I don’t think it fits into any of your drug suggestions.

The only thing nicotine is used for other than the one we all know is as an insecticide.
We all know why it is not classed as illegal in the forms it is available.
As for good effects I know of only one and that is that the brain likes the way it helps it organise itself. This being the main reason people find it difficult to quit.

I’m going to have to research the rest.

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Date: 5/11/2015 08:29:29
From: roughbarked
ID: 797295
Subject: re: Nicotine?

roughbarked said:


mollwollfumble said:

What do you know about nicotine?

How does it survive being burnt?
Why doesn’t its effectiveness drop off with time?
Why do I never hear of anyone dying from a nicotine overdose?
Why isn’t it sold as an illegal drug?
Are all the good effects of smoking due to nicotine?
What type of drug is it? analgesic? muscle relaxant? antidepressant?

They are all good questions. I don’t think it fits into any of your drug suggestions.

The only thing nicotine is used for other than the one we all know is as an insecticide.
We all know why it is not classed as illegal in the forms it is available.
As for good effects I know of only one and that is that the brain likes the way it helps it organise itself. This being the main reason people find it difficult to quit.

I’m going to have to research the rest.


Searching nicotine toxicity gave me only the one result.
https://en.wikipedia.org/wiki/Nicotine_poisoning

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Date: 5/11/2015 08:35:17
From: poikilotherm
ID: 797296
Subject: re: Nicotine?

roughbarked said:


roughbarked said:

mollwollfumble said:

What do you know about nicotine?

How does it survive being burnt?
Why doesn’t its effectiveness drop off with time?
Why do I never hear of anyone dying from a nicotine overdose?
Why isn’t it sold as an illegal drug?
Are all the good effects of smoking due to nicotine?
What type of drug is it? analgesic? muscle relaxant? antidepressant?

They are all good questions. I don’t think it fits into any of your drug suggestions.

The only thing nicotine is used for other than the one we all know is as an insecticide.
We all know why it is not classed as illegal in the forms it is available.
As for good effects I know of only one and that is that the brain likes the way it helps it organise itself. This being the main reason people find it difficult to quit.

I’m going to have to research the rest.


Searching nicotine toxicity gave me only the one result.
https://en.wikipedia.org/wiki/Nicotine_poisoning

No it didn’t.

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Date: 5/11/2015 08:41:02
From: roughbarked
ID: 797298
Subject: re: Nicotine?

poikilotherm said:


roughbarked said:

roughbarked said:

They are all good questions. I don’t think it fits into any of your drug suggestions.

The only thing nicotine is used for other than the one we all know is as an insecticide.
We all know why it is not classed as illegal in the forms it is available.
As for good effects I know of only one and that is that the brain likes the way it helps it organise itself. This being the main reason people find it difficult to quit.

I’m going to have to research the rest.


Searching nicotine toxicity gave me only the one result.
https://en.wikipedia.org/wiki/Nicotine_poisoning

No it didn’t.

;)

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Date: 5/11/2015 09:20:45
From: Rule 303
ID: 797299
Subject: re: Nicotine?

There is some evidence that smoking may have an anti-depressant effect. Whether it’s the Nicotine or another compound released by burning the Tobacco leaves is not clear.

Also:

BJM Article said:

Nicotine’s action on the reward system has long been believed to produce drug induced feelings of pleasure and, over time, addiction. Nicotine also has the effect of increasing alertness and enhancing mental performance. In the cardiovascular system, nicotine increases heart rate and blood pressure and restricts blood flow to the heart muscle. The drug stimulates the release of the hormone epinephrine (adrenaline), which further stimulates the nervous system and is responsible for part of the “kick” from nicotine. It also promotes the release of the hormone b endorphin, which inhibits pain.

It is still unclear whether smoking causes the antidepressant effects that researchers observed

Smoking may mimic effect of antidepressants

If this hypothesis turns out to be true, it might explain why just replacing the nicotine (by patches / gum etc) is not terribly effective to help people stop smoking when compared to some anti-depressant drugs.

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Date: 5/11/2015 09:43:54
From: Bubblecar
ID: 797302
Subject: re: Nicotine?

>Why do I never hear of anyone dying from a nicotine overdose?

I’d imagine it’s because nicotine is usually taken by smoking or inhaling vapour, and people who’ve overdosed will feel far too ill to keep on doing it before it builds up to lethal levels.

Even a mild nicotine overdose can be a very unpleasant sensation (involving dizziness, nausea, headaches and a need to sleep it off etc).

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Date: 5/11/2015 09:47:23
From: btm
ID: 797304
Subject: re: Nicotine?

I’ve read case reports of people dying from nicotine poisoning, most notably children/infants after eating cigarette butts. In the first quarter to half of last century nicotine was used as a pesticide; I’ve read of murderers using it as their weapon.

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Date: 5/11/2015 11:10:42
From: Cymek
ID: 797328
Subject: re: Nicotine?

I do remember hearing from patients at Graylands when I did a work placement there that it helped calm them down and keep some symptoms at bay. Lots of people claim it helps them focus and isn’t it used as a proxy diet helper as instead of eating I’ll have a smoke

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Date: 5/11/2015 19:34:56
From: mollwollfumble
ID: 797605
Subject: re: Nicotine?

roughbarked said:


roughbarked said:

mollwollfumble said:

What do you know about nicotine?

How does it survive being burnt?
Why doesn’t its effectiveness drop off with time?
Why do I never hear of anyone dying from a nicotine overdose?
Why isn’t it sold as an illegal drug?
Are all the good effects of smoking due to nicotine?
What type of drug is it? analgesic? muscle relaxant? antidepressant?

They are all good questions. I don’t think it fits into any of your drug suggestions.

The only thing nicotine is used for other than the one we all know is as an insecticide.
We all know why it is not classed as illegal in the forms it is available.
As for good effects I know of only one and that is that the brain likes the way it helps it organise itself. This being the main reason people find it difficult to quit.

I’m going to have to research the rest.


Searching nicotine toxicity gave me only the one result.
https://en.wikipedia.org/wiki/Nicotine_poisoning

Let’s see:
> The estimated lower limit of a lethal dose of nicotine has been reported as between 500 and 1000 mg … 6.5–13 mg/kg orally.

Compare other active chemicals:
Caffeine LD50 for humans 150 to 200 mg/kg.
Aspirin (for rats) 200 mg/kg.
Morphine lower limit of a lethal dose 200 mg/human.

> Nicotine is both a stimulant and a relaxant. Users report feelings of relaxation, sharpness, calmness, and alertness.

Similar to tea perhaps, relaxation followed by alertness.

> Why doesn’t it burn?

Pyrolysis perhaps, it evaporates before it reaches temperatures high enough to burn.

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Date: 6/11/2015 11:03:14
From: Peak Warming Man
ID: 797959
Subject: re: Nicotine?

I’ll put this here although it’s a bot OT but closeish.

——————————————————————————————————-
Queensland scientists say they have solved an evolutionary riddle spanning 750,000 years that could provide important answers on how to grow crops in space.

Professor Peter Waterhouse and Dr Julia Bally from Queensland University of Technology said they discovered the Australian native tobacco plant, also known as Pitjuri, had thrown out its immune system in favour of rapid reproduction and over-sized seeds.

In order to work out how the plant achieved this unique adaptation, the scientists mapped the gene fault that turned off the plant’s immune system.

They said that discovery would open up whole new worlds of research in medicine and food production.

Professor Waterhouse described the Pitjuri plant as extraordinary.

“They’ve got this gene that’s been switched off and this is giving it these magical properties,” he said.

The absence of an immune system makes the tobacco plant an exceptional subject for experiments.

“It just has this fabulous property of taking a gene in from virtually everywhere and it accepts it and it expresses it so it rapidly, speeds up the research,” he said.

Researchers testing genes or developing antibodies can get results in four days instead of a year.

The Pitjuri plant was recently used to develop a vaccine for the Ebola virus.

http://www.abc.net.au/news/2015-11-03/pitjuri-plant-genes-offer-new-hope-food-production/6908908
——————————————————————————-

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Date: 6/11/2015 13:05:16
From: roughbarked
ID: 798017
Subject: re: Nicotine?

Peak Warming Man said:


I’ll put this here although it’s a bot OT but closeish.

——————————————————————————-

Pitjuri is Solanaceae but isn’t actually Nicotina.

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Date: 6/11/2015 13:06:35
From: roughbarked
ID: 798019
Subject: re: Nicotine?

Peak Warming Man said:


I’ll put this here although it’s a bot OT but closeish.

——————————————————————————-

Pitjuri is Solanaceae but isn’t actually Nicotiana.

Fixed.

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