Our Best View Yet Of Molecules Moving Inside Living Cells

A new microscope developed at the Marine Biological Laboratory in Woods Hole, Massachusetts is allowing scientists track the position and orientation of individual molecules in living cells. It has the potential to reveal unknown aspects of molecular behaviour, including those that turn cells into agents of disease.

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CrazyNeutrino said:

Our Best View Yet Of Molecules Moving Inside Living Cells

A new microscope developed at the Marine Biological Laboratory in Woods Hole, Massachusetts is allowing scientists track the position and orientation of individual molecules in living cells. It has the potential to reveal unknown aspects of molecular behaviour, including those that turn cells into agents of disease.

more…

“Dubbed the “instantaneous fluorescence polarization” microscope”

“these assemblies are much finer than the resolution limit of the light microscope.”

“catch a glimpse of the microscopic particles by using polarised light, a property of light that’s not visible to the human eye. After labelling DNA and actin molecules with fluorescence, the researchers tracked the movements of these tiny particles in living human skin cells.”

Colleagues at CSIRO were doing similar things to view movements in fluids, but this is on a much smaller scale, I don’t see how can view the fluorescence on a sub-light length scale. Do you understand this? Deconvolution?

mollwollfumble said:

CrazyNeutrino said:

Our Best View Yet Of Molecules Moving Inside Living Cells

A new microscope developed at the Marine Biological Laboratory in Woods Hole, Massachusetts is allowing scientists track the position and orientation of individual molecules in living cells. It has the potential to reveal unknown aspects of molecular behaviour, including those that turn cells into agents of disease.

more…

“Dubbed the “instantaneous fluorescence polarization” microscope”

“these assemblies are much finer than the resolution limit of the light microscope.”

“catch a glimpse of the microscopic particles by using polarised light, a property of light that’s not visible to the human eye. After labelling DNA and actin molecules with fluorescence, the researchers tracked the movements of these tiny particles in living human skin cells.”

Colleagues at CSIRO were doing similar things to view movements in fluids, but this is on a much smaller scale, I don’t see how can view the fluorescence on a sub-light length scale. Do you understand this? Deconvolution?

After labelling DNA and actin molecules with fluorescence, the researchers tracked the movements of these tiny particles in living human skin cells.

I would like to see a documentary on the whole process, then I might have a better idea on how they do it.

Documentaries on all scientific studies and discoveries on YouTube would be awesome.

> Documentaries on all scientific studies and discoveries on YouTube would be awesome.

Agree. The scientists producing these press releases for news publication probably already have either a powerpoint presentation (which could be turned into a video), an A1 size poster (dotto), or a video of the discovery. One or two of these is necessary for presentation at a conference.

That said, it would even be awesome if I could produce YouTube videos of my own discoveries.