Date: 8/02/2017 10:13:19
From: buffy
ID: 1021936
Subject: Amblyopia (lazy eye)

If this research is right, this could be truly ground breaking in actually curing lazy eyes. It basically turns off the retina with anaesthetic and then starts it up in a sort of reboot.

“Normal development of the visual cortex depends critically on early life visual experience. In humans, a disparity in the quality of vision between two eyes during infancy or early childhood leads to a visual impairment called amblyopia. In animal models, amblyopia can be induced early in life using a brief period of monocular deprivation via eyelid closure. Here we show in two evolutionarily divergent species that experimental amblyopia can be rapidly corrected if binocular visual experience is restored after temporarily silencing the retinas with a local anesthetic. These findings point the way to an approach for clinical management of amblyopia with advantages over the current standard of care.”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150384/

So far seems to work in mice and kittens. You would need to remove the original cause of the amblyopia too, usually it’s a big difference between the prescription between the eyes, so full spectacle correction would be required straight after you straightened out the neural stuff. Sometimes it’s a turned eye, so you would need to fix that surgically.

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Date: 8/02/2017 10:41:06
From: Bubblecar
ID: 1021945
Subject: re: Amblyopia (lazy eye)

Good news.

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Date: 8/02/2017 12:49:05
From: mollwollfumble
ID: 1021997
Subject: re: Amblyopia (lazy eye)

So this treatment is specifically aimed at children?
Rather than old people.

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Date: 8/02/2017 12:57:25
From: roughbarked
ID: 1021999
Subject: re: Amblyopia (lazy eye)

mollwollfumble said:


So this treatment is specifically aimed at children?
Rather than old people.

Children have time to heal.

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Date: 8/02/2017 13:15:00
From: buffy
ID: 1022009
Subject: re: Amblyopia (lazy eye)

mollwollfumble said:


So this treatment is specifically aimed at children?
Rather than old people.

Not necessarily. If it is a “reboot” it might work in older systems too. It’s a long way off trialling in people yet, but the concept is very inviting.

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