Date: 25/07/2017 09:57:45
From: dv
ID: 1093956
Subject: Consanguinity

The expected amount of autosomal DNA shared between people who are related to each other can be worked out by assuming that each parent contributes half. (In reality there is some statistical range but leave that to one side…)

According to my understanding, a child whose parents are brother and sister could expect to share 62.5% of autosomal DNA with either of his or her parents. Do you agree with this analysis?

Can you contrive any circumstances in which two people would share 37.5% of DNA?

Reply Quote

Date: 25/07/2017 10:33:31
From: Cymek
ID: 1093960
Subject: re: Consanguinity

dv said:


The expected amount of autosomal DNA shared between people who are related to each other can be worked out by assuming that each parent contributes half. (In reality there is some statistical range but leave that to one side…)

According to my understanding, a child whose parents are brother and sister could expect to share 62.5% of autosomal DNA with either of his or her parents. Do you agree with this analysis?

Can you contrive any circumstances in which two people would share 37.5% of DNA?

One of them is a chimera ?

Reply Quote

Date: 25/07/2017 11:41:28
From: Speedy
ID: 1093978
Subject: re: Consanguinity

Cymek said:


One of them is a chimera ?

+1

Reply Quote

Date: 25/07/2017 12:29:32
From: Witty Rejoinder
ID: 1094018
Subject: re: Consanguinity

dv said:

Can you contrive any circumstances in which two people would share 37.5% of DNA?

How about half siblings?

Reply Quote

Date: 25/07/2017 12:35:27
From: dv
ID: 1094020
Subject: re: Consanguinity

Witty Rejoinder said:


dv said:

Can you contrive any circumstances in which two people would share 37.5% of DNA?

How about half siblings?

That seems to be 25%

Reply Quote

Date: 25/07/2017 12:43:54
From: Arts
ID: 1094024
Subject: re: Consanguinity

dv said:


Witty Rejoinder said:

dv said:

Can you contrive any circumstances in which two people would share 37.5% of DNA?

How about half siblings?

That seems to be 25%


the offspring of first cousins

Reply Quote

Date: 25/07/2017 12:46:17
From: dv
ID: 1094026
Subject: re: Consanguinity

Arts said:


dv said:

Witty Rejoinder said:

How about half siblings?

That seems to be 25%


the offspring of first cousins

The electric internet says “3/4 siblings or sibling-cousins” so I just need to work out what that means.

Reply Quote

Date: 25/07/2017 12:49:08
From: dv
ID: 1094027
Subject: re: Consanguinity

And WP says

Three-quarter
Three-quarter siblings have one common parent, while their unshared parents have a mean consanguinity of 50%. This means the unshared parents are either siblings or parent and child (similar terminology is used in horse breeding, where it occurs more frequently). Three-quarter siblings share more genes than half siblings, but fewer than full siblings.

“Sibling cousins” are those who have the same mother with their fathers being brothers or cousins or who share the same father with their mothers being sisters or cousins. This is a broader category than, but inclusive of, the 3/4 sibling above.

—-

Wow, it’s just a whole world of families out there

Reply Quote

Date: 25/07/2017 12:49:17
From: furious
ID: 1094028
Subject: re: Consanguinity

Two people who share three out of four grandparents?

Reply Quote

Date: 25/07/2017 12:59:30
From: party_pants
ID: 1094031
Subject: re: Consanguinity

dv said:


And WP says

Three-quarter
Three-quarter siblings have one common parent, while their unshared parents have a mean consanguinity of 50%. This means the unshared parents are either siblings or parent and child (similar terminology is used in horse breeding, where it occurs more frequently). Three-quarter siblings share more genes than half siblings, but fewer than full siblings.

“Sibling cousins” are those who have the same mother with their fathers being brothers or cousins or who share the same father with their mothers being sisters or cousins. This is a broader category than, but inclusive of, the 3/4 sibling above.

—-

Wow, it’s just a whole world of families out there

Unless you’re a royal or a horse breeder it probably isn’t that important.

Reply Quote

Date: 25/07/2017 13:01:25
From: dv
ID: 1094033
Subject: re: Consanguinity

party_pants said:


dv said:

And WP says

Three-quarter
Three-quarter siblings have one common parent, while their unshared parents have a mean consanguinity of 50%. This means the unshared parents are either siblings or parent and child (similar terminology is used in horse breeding, where it occurs more frequently). Three-quarter siblings share more genes than half siblings, but fewer than full siblings.

“Sibling cousins” are those who have the same mother with their fathers being brothers or cousins or who share the same father with their mothers being sisters or cousins. This is a broader category than, but inclusive of, the 3/4 sibling above.

—-

Wow, it’s just a whole world of families out there

Unless you’re a royal or a horse breeder it probably isn’t that important.

Reply Quote

Date: 26/07/2017 10:35:44
From: OCDC
ID: 1094421
Subject: re: Consanguinity

dv said:

Can you contrive any circumstances in which two people would share 37.5% of DNA?
Two children who have one parent in common and whose other parents were siblings.

Reply Quote

Date: 27/07/2017 06:28:48
From: mollwollfumble
ID: 1094684
Subject: re: Consanguinity

dv said:


The expected amount of autosomal DNA shared between people who are related to each other can be worked out by assuming that each parent contributes half. (In reality there is some statistical range but leave that to one side…)

According to my understanding, a child whose parents are brother and sister could expect to share 62.5% of autosomal DNA with either of his or her parents. Do you agree with this analysis?

Can you contrive any circumstances in which two people would share 37.5% of DNA?

Where did you get the 62.5%?

A person shares roughly 50% of autosomal DNA with each parent, and roughly 50% of autosomal DNA with each sibling. Aunt/uncle with nephew/niece would tend to be 25% and first cousin would be roughly half that.

If brother and sister have a child (presumably out of wedlock) then, um … I’ll get out the coloured crayons to work it out.
If father and daughter have a child, ditto.

Ah, wait, a key word that requires definition is “share”. Consider the case where person 1 has genetic code AB and person 2 has genetic code AA. Depending on the definition of “share”, we could have person 1 sharing 50% of DNA with person 2, but person 2 sharing 100% of DNA with person 1. It that a reasonable interpretation?

Reply Quote

Date: 27/07/2017 12:00:40
From: mollwollfumble
ID: 1094787
Subject: re: Consanguinity

dv said:


And WP says

Three-quarter
Three-quarter siblings have one common parent, while their unshared parents have a mean consanguinity of 50%. This means the unshared parents are either siblings or parent and child (similar terminology is used in horse breeding, where it occurs more frequently). Three-quarter siblings share more genes than half siblings, but fewer than full siblings.

“Sibling cousins” are those who have the same mother with their fathers being brothers or cousins or who share the same father with their mothers being sisters or cousins. This is a broader category than, but inclusive of, the 3/4 sibling above.

—-

Wow, it’s just a whole world of families out there

Fascinating.

Reply Quote