This is worth reposting. It’s how bacteria export proteins.
https://mobile.the-scientist.com/article/53504/image-of-the-day-bacterial-flagella
mollwollfumble said:
This is worth reposting. It’s how bacteria export proteins.https://mobile.the-scientist.com/article/53504/image-of-the-day-bacterial-flagella
I’ve heard of engineers copying biological processes in their work, but I didn’t know that bacteria copy human mechanical engineering processes.
Buffy may be interested in this one.
A team of physicians and researchers reported earlier this month (April 4) in Science Translational Medicine that they successfully treated advanced dry age-related macular degeneration with retinal implants grown from stem cells. Four patients received the implant, which consists of a layer of retinal pigment epithelium cells grown from human embryonic stem cell atop an ultra-thin supportive synthetic parylene structure. One year later, three of the four patients had improvements in vision, and none of the patients had progression of vision loss.
“This implant has the potential to stop the progression of the disease or even improve patients’ vision,” says Amir Kashani, a clinical ophthalmologist at the University of Southern California, in a statement. “Proving its safety in humans is the first step in accomplishing that goal.”
A. Kashani et al., “A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration,” Sci Transl Med, doi:10.1126/scitranslmed.aao4097, 2018.
mollwollfumble said:
Buffy may be interested in this one.A team of physicians and researchers reported earlier this month (April 4) in Science Translational Medicine that they successfully treated advanced dry age-related macular degeneration with retinal implants grown from stem cells. Four patients received the implant, which consists of a layer of retinal pigment epithelium cells grown from human embryonic stem cell atop an ultra-thin supportive synthetic parylene structure. One year later, three of the four patients had improvements in vision, and none of the patients had progression of vision loss.
“This implant has the potential to stop the progression of the disease or even improve patients’ vision,” says Amir Kashani, a clinical ophthalmologist at the University of Southern California, in a statement. “Proving its safety in humans is the first step in accomplishing that goal.”
A. Kashani et al., “A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration,” Sci Transl Med, doi:10.1126/scitranslmed.aao4097, 2018.
And another for buffy.
Severe Plasmodium falciparum malaria infections can often be diagnosed by examining a patient’s retina because the disease can cause changes in the blood vessels and the retina’s color. The prognostic significance of this outcome was not clear until recently, however. Researchers reported last month (March 26) in eLife that certain changes in the retina’s fovea—namely, foveal whitening and orange, defective blood vessels—are strongly associated with death in patients with cerebral malaria. The findings may provide a useful marker for diagnosing severe infections, the researchers write.
V. Berrera et al., “Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina,” eLife, doi:10.7554/eLife.32208, 2018.
mollwollfumble said:
mollwollfumble said:
Buffy may be interested in this one.A team of physicians and researchers reported earlier this month (April 4) in Science Translational Medicine that they successfully treated advanced dry age-related macular degeneration with retinal implants grown from stem cells. Four patients received the implant, which consists of a layer of retinal pigment epithelium cells grown from human embryonic stem cell atop an ultra-thin supportive synthetic parylene structure. One year later, three of the four patients had improvements in vision, and none of the patients had progression of vision loss.
“This implant has the potential to stop the progression of the disease or even improve patients’ vision,” says Amir Kashani, a clinical ophthalmologist at the University of Southern California, in a statement. “Proving its safety in humans is the first step in accomplishing that goal.”
A. Kashani et al., “A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration,” Sci Transl Med, doi:10.1126/scitranslmed.aao4097, 2018.
And another for buffy.
Severe Plasmodium falciparum malaria infections can often be diagnosed by examining a patient’s retina because the disease can cause changes in the blood vessels and the retina’s color. The prognostic significance of this outcome was not clear until recently, however. Researchers reported last month (March 26) in eLife that certain changes in the retina’s fovea—namely, foveal whitening and orange, defective blood vessels—are strongly associated with death in patients with cerebral malaria. The findings may provide a useful marker for diagnosing severe infections, the researchers write.
V. Berrera et al., “Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina,” eLife, doi:10.7554/eLife.32208, 2018.
What about Lyme Disease? )-:
Ogmog said:
mollwollfumble said:
mollwollfumble said:
Buffy may be interested in this one.A team of physicians and researchers reported earlier this month (April 4) in Science Translational Medicine that they successfully treated advanced dry age-related macular degeneration with retinal implants grown from stem cells. Four patients received the implant, which consists of a layer of retinal pigment epithelium cells grown from human embryonic stem cell atop an ultra-thin supportive synthetic parylene structure. One year later, three of the four patients had improvements in vision, and none of the patients had progression of vision loss.
“This implant has the potential to stop the progression of the disease or even improve patients’ vision,” says Amir Kashani, a clinical ophthalmologist at the University of Southern California, in a statement. “Proving its safety in humans is the first step in accomplishing that goal.”
A. Kashani et al., “A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration,” Sci Transl Med, doi:10.1126/scitranslmed.aao4097, 2018.
And another for buffy.
Severe Plasmodium falciparum malaria infections can often be diagnosed by examining a patient’s retina because the disease can cause changes in the blood vessels and the retina’s color. The prognostic significance of this outcome was not clear until recently, however. Researchers reported last month (March 26) in eLife that certain changes in the retina’s fovea—namely, foveal whitening and orange, defective blood vessels—are strongly associated with death in patients with cerebral malaria. The findings may provide a useful marker for diagnosing severe infections, the researchers write.
V. Berrera et al., “Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina,” eLife, doi:10.7554/eLife.32208, 2018.
What about Lyme Disease? )-:
No lime disease in Australia.
mollwollfumble said:
Buffy may be interested in this one.A team of physicians and researchers reported earlier this month (April 4) in Science Translational Medicine that they successfully treated advanced dry age-related macular degeneration with retinal implants grown from stem cells. Four patients received the implant, which consists of a layer of retinal pigment epithelium cells grown from human embryonic stem cell atop an ultra-thin supportive synthetic parylene structure. One year later, three of the four patients had improvements in vision, and none of the patients had progression of vision loss.
“This implant has the potential to stop the progression of the disease or even improve patients’ vision,” says Amir Kashani, a clinical ophthalmologist at the University of Southern California, in a statement. “Proving its safety in humans is the first step in accomplishing that goal.”
A. Kashani et al., “A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration,” Sci Transl Med, doi:10.1126/scitranslmed.aao4097, 2018.
Dry macular degeneration does not really progress fast unless it “converts” to wet type. So no progression over the year is going to be difficult to assign to the implant.
I’ve started to look at the paper. Two people’s eyes improved a bit, one quite a bit. But that person’s untreated eye also improved quite a bit over the year. Suggests to me that the unpredictability of mac degen is, well, unpredictable and makes interpreting this sort of research very difficult.
(The paper is behind a paywall, but you can get to it with Sci Hub at http://sci-hub.tw/ You need the doi of the paper, which is: 10.1126/scitranslmed.aao4097 )
https://www.sciencedirect.com/science/article/pii/S2352771416300039
Seems to be the latest on Lyme disease and Australia. 2016. Still not here.
Pity about a year not being a long enough test for macular.
Brain of a female mosquito (Aedes aegypti). Can this explain how mosquitos can outthink humans? Like, for instance large in the region found in predators?
buffy said:
https://www.sciencedirect.com/science/article/pii/S2352771416300039Seems to be the latest on Lyme disease and Australia. 2016. Still not here.
I know someone with Chronic Lyme disease
and it’s the most devious & devastating malady ever;
constantly morphing and mimicking other incurable diseases
and yet remains almost impossible to detect/diagnose let alone treat.
So the question stands;
Does that diagram, and the science behind it, apply?
Ogmog said:
buffy said:
https://www.sciencedirect.com/science/article/pii/S2352771416300039Seems to be the latest on Lyme disease and Australia. 2016. Still not here.
“…but for the grace of god…”I know someone with Chronic Lyme disease
and it’s the most devious & devastating malady ever;
constantly morphing and mimicking other incurable diseases
and yet remains almost impossible to detect/diagnose let alone treat.So the question stands;
Does that diagram, and the science behind it, apply?
No lyme disease here, yet.
so bacteria only exists in Australia?
Ogmog said:
so bacteria only exists in Australia?
no.
roughbarked said:
Ogmog said:so bacteria only exists in Australia?
no.
Specific bacteria do and hopefully specfic bacteria do not.
Ogmog said:
buffy said:
https://www.sciencedirect.com/science/article/pii/S2352771416300039Seems to be the latest on Lyme disease and Australia. 2016. Still not here.
“…but for the grace of god…”I know someone with Chronic Lyme disease
and it’s the most devious & devastating malady ever;
constantly morphing and mimicking other incurable diseases
and yet remains almost impossible to detect/diagnose let alone treat.So the question stands;
Does that diagram, and the science behind it, apply?
The most they will say is it is Lyme disease LIKE. It is commonly thought that something is going on with tics, but they are not sure and it will cost dollars to find out (plus it is a small market and research is expensive).
PermeateFree said:
Ogmog said:
buffy said:
https://www.sciencedirect.com/science/article/pii/S2352771416300039Seems to be the latest on Lyme disease and Australia. 2016. Still not here.
“…but for the grace of god…”I know someone with Chronic Lyme disease
and it’s the most devious & devastating malady ever;
constantly morphing and mimicking other incurable diseases
and yet remains almost impossible to detect/diagnose let alone treat.So the question stands;
Does that diagram, and the science behind it, apply?The most they will say is it is Lyme disease LIKE. It is commonly thought that something is going on with tics, but they are not sure and it will cost dollars to find out (plus it is a small market and research is expensive).
Things seldom stay as they are…
btw, there are 35,000 NEW Cases a year of Lyme Disease..
..and that’s ONLY the cases that have been diagnosed, which
as stated, is next to impossible using currant conventional tests. /-: