Great News! There IS hope for the forum

>>A fascinating new study from researchers at Temple University has successfully reversed cognitive impairments in mice with dementia. The research utilized a 20-year-old asthma drug to treat the animals and the hope is to fast track clinical trials to verify the results in human subjects.<<

https://newatlas.com/dementia-alzheimers-tau-reversed-mice/55011

PermeateFree said:

Great News! There IS hope for the forum

>>A fascinating new study from researchers at Temple University has successfully reversed cognitive impairments in mice with dementia. The research utilized a 20-year-old asthma drug to treat the animals and the hope is to fast track clinical trials to verify the results in human subjects.<<

https://newatlas.com/dementia-alzheimers-tau-reversed-mice/55011

You posted this before did you forget ?

Read it but I still don’t know what tau is?

Peak Warming Man said:

Read it but I still don’t know what tau is?

Or who is tau.

For a somewhat change of subject should Euthanasia include dementia so if you get it and no cure is in sight (assuming it’s reversible rather than preventable). You can have a living will euthanize me if I get dementia.

Cymek said:

For a somewhat change of subject should Euthanasia include dementia so if you get it and no cure is in sight (assuming it’s reversible rather than preventable). You can have a living will euthanize me if I get dementia.

That’s an excellent question, there are good arguments both for and against.

> The research looked to a drug called zileuton, known to inhibit leukotriene formation, and safely administered to patients with asthma for over 20 years.

So I suppose the first step would be to look for a negative correlation between zileutron users and alzheimer sufferers?

https://link.springer.com/article/10.1007/s12035-018-1124-7

SCIENCE said:

https://link.springer.com/article/10.1007/s12035-018-1124-7

If leukotrienes are there to protect nerve cells, then how did zileuton come to be approved for asthma?

mollwollfumble said:

SCIENCE said:

https://link.springer.com/article/10.1007/s12035-018-1124-7

If leukotrienes are there to protect nerve cells, then how did zileuton come to be approved for asthma?

They do these things called clinical trials…you may have heard of them.

And it’s specific for a certain leukotriene involved in asthma.

actually wrong drug…as you were. but clinical trials bit still relevant.

I’ll get back to what I should be doing …

poikilotherm said:

actually wrong drug…as you were. but clinical trials bit still relevant.

I’ll get back to what I should be doing …

They pay quite well, not sure of the detriments to your health though

poikilotherm said:

actually wrong drug…as you were. but clinical trials bit still relevant.

I’ll get back to what I should be doing …

poikilotherm said:

And it’s specific for a certain leukotriene involved in asthma.

Ah, I see. That makes a big difference.