captain_spalding said:

dv said:

captain_spalding said:

I did. It’s very concerning.

State of the Evidence: MMR Vaccine

The MMR vaccine has been studied regarding autism, and the reviews from IOM and AHRQ maintain with a high strength of evidence that there is no association with autism spectrum disorders based on observational evidence only.

However, in 2012, the IOM reviewed the published MMR-autism studies and found that all but four of them had “serious methodological limitations,” and the IOM gave them no weight. The remaining four studies and a few similar studies published since also have all been criticized for serious methodological flaws. Furthermore, they are all retrospective epidemiological studies which cannot prove causation, fail to account for potential vulnerable subgroups, and fail to account for mechanistic and other evidence linking vaccines with autism.

Many of the retrospective studies utilized, such as the 2002 New England Journal of Medicine study on the Denmark population, may be unreliable for the U.S. population. Children in these studies receive vaccines based on foreign vaccination schedules that differ from the schedule in the U.S. As outlined in the 2013 IOM report on the childhood immunization schedule, “there are few comparative studies evaluating the safety of different vaccine schedules,” but “there are cases in which the risk of adverse events can depend on the vaccination schedule used and factors such as timing and adjuvants should be studied with appropriate design methods.”

For example, the MMR vaccine does not contain aluminum. However, other infant vaccines have aluminum content ranging from 0.25 mg to 0.625 mg per dose (DTaP has the highest content). One analysis found that the 2019 CDC vaccine schedule resulted in 4.925 mg of total vaccine-related aluminum exposure by age 18 months. There is evidence in the U.S. of a positive association between vaccine-related aluminum exposure and persistent asthma. Evidence from a large Danish cohort study reported no increased risk for neurodevelopmental disorders with early childhood exposure to aluminum-adsorbed vaccines, but a detailed review of the supplementary tables shows some higher event rates of neurodevelopmental conditions with moderate aluminum exposure (Supplement Figure 11 — though a dose response was not evident) and a statistically significant 67% increased risk of Asperger’s syndrome per 1 mg increase in aluminum exposure among children born between 2007 and 2018 (Supplement Figure 4). Together, these findings warrant further investigation of aluminum exposures (high, low, and none) for a variety of childhood chronic diseases, including autism.

I took it as, “OK, calm down, tinfoil brigade’, we’ll take a look at whatever comes along about vaccines, and, if it holds up to scrutiny and seems to have some scientific value, we’ll tell you about it here”.

Not “we’re throwing the baby out with the bathwater, and we think that the wackos are on to something”.

pretty sure “just asking questions” is an innocuous wish to simply be more personally informed Abbie inoculations, there’s no agenda and no harm